Oxycodone is actually a semisynthetic opioid medication with strong suffering-relieving properties that may be applied To ease severe soreness that may be unresponsive to much less potent soreness-relieving medicines (analgesics). It could be addictive and trigger Bodily dependence.
Extreme adverse outcomes including respiratory depression is usually addressed Along with the opioid antagonist naloxone.[Ref]
Opioid analgesics, like oxycodone HCl, can prolong labor by way of steps which quickly lessen the toughness, length and frequency of uterine contractions. On the other hand, this result is not constant and may be offset by an increased price of cervical dilation, which tends to shorten labor. Keep track of neonates exposed to opioid analgesics throughout labor for indications of extra sedation and respiratory depression.
If a CYP3A4 inhibitor is discontinued, think about expanding the oxycodone HCl dosage right until secure drug consequences are attained. Observe for indications of opioid withdrawal.
Go over the availability of naloxone for your unexpected emergency treatment method of opioid overdose While using the client and caregiver and assess the possible want for entry to naloxone, both equally when initiating and renewing cure with oxycodone HCl tablets [see Warnings and Safeguards (five.three), Client Counseling Info (seventeen)]. Inform people and caregivers about the different means to acquire naloxone as permitted by specific point out naloxone dispensing and prescribing requirements or rules (e.
Cytochrome P450 3A4 Conversation The concomitant use of oxycodone with all cytochrome P450 3A4 inhibitors may result in an increase in oxycodone plasma concentrations, which could maximize or prolong adverse reactions and will induce possibly lethal respiratory depression.
Check patients which has a history of seizure Issues for worsened seizure Regulate for the duration of oxycodone HCl therapy.
Oxycodone and Oxycontin are entire agonists for the mu receptor. Because of this they don't Have a very ceiling effect for pain reduction, so bigger dosages are connected with amplified discomfort relief.
Stay away from medication glitches. Constantly Examine the brand and toughness of oxycodone you can get within the pharmacy.
Just take OxyContin accurately as prescribed. Stick to the Instructions with your prescription label and browse all medication guides. Never use oxycodone in larger sized quantities, or for lengthier than prescribed. Connect with your Health care company Should the dose that you are getting isn't going to Regulate your suffering.
Respiratory despair is much more likely to occur in the course of the initially one to 3 days of oxycodone click here or Oxycontin therapy, following a dosage raise, or if far too much oxycodone or Oxycontin is taken.
Administration of supplemental analgesia for breakthrough or incident discomfort and titration of the whole every day dose of oxycodone HCl tablets may very well be important, particularly in patients who definitely have disorder states that happen to be shifting speedily.
You'll have breathing difficulties or withdrawal signs if you start or halt having particular other medicines. Inform your medical doctor if Additionally you use an antibiotic, antifungal medication, coronary heart or hypertension medication, seizure medication, or medicine to deal with HIV or hepatitis C.
Notify your medical doctor When you are breastfeeding or planning to breastfeed, as this medicine could hurt your baby. Breastfeeding will not be encouraged for the duration of treatment method with OxyContin.